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KMID : 0376219790160010037
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Chonnam Medical Journal
1979 Volume.16 No. 1 p.37 ~ p.42
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Survey on the antibiotic resistance of bacteria isolated from rural communities of Chonnam province
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Abstract
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A total of 108 strains (Staphylococcus aureus, 18; Salmonella, 7; Shigella, 3; Escherichia coli, 80) was isolated from residents of 4 seperate rural areas of Chonnam Province mainly during last year. Minimum inhibitory concentration (MIC) of antibiotics, ampicillin(AP), chloramphenicol(CM), tetracycline(TC) erythromycin(EM), and streptomycin(SM), to each of the isolates was measured and its distribution pattern was compared each other with the following results.
1. Most of the strains isolated were comparatively susceptible to AP and the distribution of MIC was considerably narrow, i.e., no strain was observed growing on the medium containing more than l6,ug/me, while no strain was inhibited by less than 1μg/me.
2. CM showed a wide distribution of MICs ; three strains of S. aureus grew even on medium containing more than 32μg/ me, while one strain of E. coli was inhibited by 1μg/me.
3. TC was the most effect drug; several strains were inhibited even by 0.5μg/me while only one strain grew at 16,ug/me, thus most of the isolates were susceptible to less than 8,ug/mL.
4. Differences between Staphylococcus and enteric bacilli were noticeable in the MIC distribution of EM; no strain of E, coli was susceptible to less than 8μg/ne and 32μg/ne was the most frequent MIC, while no strain of S. aureus was observed growing at 16μg/ml.
5. SM was the least effective antibiotic among the ones tested; several strains grew even at 128μg/ml, while no strain was inhibited by the concentration of 1μg/ml.
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